Is the high priestess evil?

The High Priestess, along with The Dominator, is one of the two Samurai Jack villains to be Pure Evil.

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Thereof, does the high priestess mean pregnancy?

The High Priestess also has the potential to indicate that a querent is either pregnant already (unaware of it though) or will fall pregnant shortly without being aware or perhaps without 'trying'. Always follow your intuition and trust yourself to read the cards in the way that feels right to you. Are you supposed to separate the major and Minor Arcana? Regardless of whether or not you'll need to separate the Major/Minor Arcana, there's no specific amount or type of shuffling you need to do. Do it as much (or as little) as you'd like.

Regarding this, can minor and major arcana mix?

Yes, you would mix the major and minor arcana of a tarot deck when shuffling in your readings. How do you use a 22 card in a tarot deck?

Does the world mean yes or no?

If you've pulled the World card in a yes or no reading, prepare to become deeply involved in something worthwhile. The answer you seek is YES, so long as it contributes to the good of all. Is the Lovers a yes or a no? Those seeking a yes or no answer often pull the Lovers tarot card since it deals with choices and feeling uncertain about a decision. What is this? If you are at a crossroads and want to move forward in a certain direction but feel 'unsure', put all doubt to the side.